Longevity Coenzyme · Research Grade

NAD⁺ — Nicotinamide Adenine Dinucleotide

The master coenzyme behind cellular energy and healthy aging. NAD⁺ powers the reactions that keep every cell energized and is the essential cofactor for the sirtuins — the enzymes at the heart of longevity science. Its levels decline naturally with age, which is why NAD⁺ is one of the most studied molecules in the field. High-purity, research-grade, independently tested and COA-verified, made to Japan quality standards.

Cellular energyHealthy-aging scienceDNA repairLongevity pathways
NAD⁺ — Nicotinamide Adenine Dinucleotide

Why review NAD⁺ with Aeternum Life

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What is NAD⁺?

NAD⁺ (nicotinamide adenine dinucleotide, CAS 53-84-9) is a coenzyme found in every living cell — one of the most fundamental molecules in biology. It exists in two interchangeable forms, NAD⁺ and NADH, that cells continuously cycle between to carry electrons through the reactions of energy metabolism.

Beyond energy, NAD⁺ is consumed as a substrate by two important enzyme families: the sirtuins, studied in cellular maintenance and longevity signaling, and the PARPs, involved in DNA repair. Because cellular NAD⁺ levels are reported to decline with age, NAD⁺ biology has become one of the most active fields in metabolism and aging research. Aeternum Life supplies NAD⁺ as a high-purity, research-grade material, backed by a batch-specific Certificate of Analysis.

Research directions

NAD⁺ sits at the center of some of biology’s most important systems — energy, repair and longevity. Here is where it plays its role, and why it has become one of the most researched molecules in the field.

Cellular energy & mitochondria

NAD⁺ is the electron carrier that drives ATP production — the energy currency of every cell. It sits at the center of glycolysis, the TCA cycle and oxidative phosphorylation, keeping mitochondria running.

Sirtuins & longevity pathways

NAD⁺ fuels the sirtuins (SIRT1–7) — the enzymes widely known as the “longevity genes” — which govern cellular maintenance, stress resistance and metabolic health.

DNA repair (PARPs)

The PARP enzymes draw on NAD⁺ to detect and repair DNA damage, tying NAD⁺ availability directly to the cell’s ability to protect its genome.

NAD⁺ decline with age

Cellular NAD⁺ falls steadily as we age — a decline that sits at the heart of modern longevity science and NAD⁺-restoration research.

Metabolic regulation

Through its NAD⁺-dependent enzymes, NAD⁺ helps orchestrate how cells handle glucose and fat, making it a cornerstone of metabolic research.

Neuronal & cognitive research

Neurons are energy-hungry, and NAD⁺ metabolism is a growing focus in research on brain energy, resilience and healthy aging.

For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.

NAD⁺ documentation

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Handling & Storage

Guidance for handling NAD⁺ as a laboratory research material.

Storage

Store lyophilized NAD⁺ cold and protected from light, sealed and dry until use.

Laboratory handling

Handle NAD⁺ according to standard laboratory practice for research materials.

Documentation

Published batch documentation is linked when a matching record is available.

NAD⁺ is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.

Specifications

Name
NAD⁺ (Nicotinamide Adenine Dinucleotide)
CAS
53-84-9
Appearance
White to pale-yellow lyophilized powder
Size
500 mg
Purity
≥ 99% (HPLC, see COA)
Storage
Store at 2–8°C, protect from light

For research use. Not intended to diagnose, treat, cure or prevent any disease.

Frequently asked questions

What is NAD⁺ studied for?

In the research literature NAD⁺ is studied mainly in relation to cellular energy metabolism, the sirtuin and PARP enzymes, DNA repair and aging. Aeternum Life shares these only as areas of research interest, not as claims of any effect.

Do NAD⁺ levels change with age?

Research across many models reports that tissue NAD⁺ levels tend to decline with age, which is a central question in NAD⁺ metabolism research. This is background biology, not a claim about any product effect.

Is NAD⁺ for human use?

No. Aeternum Life supplies NAD⁺ strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.

Is a COA available for NAD⁺?

Published COA records are available by product and batch when a matching record exists. Laboratory and verification details appear only when stated in that record.

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The current catalog contains laboratory research materials and research accessories. Research materials are not medicines or dietary supplements and are not intended for human or veterinary consumption. Product pages show the intended-use status and the batch documentation currently available.

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