Epitalon — The Telomere Peptide
Epitalon is longevity research’s most famous four-letter peptide. A tiny tetrapeptide (Ala-Glu-Asp-Gly), it’s studied around one of aging science’s biggest questions: telomeres, the protective caps on your DNA that shorten as cells divide. It’s also tied to the pineal gland and the body’s day-night rhythm. Every batch is independently third-party tested for purity and ships with its own certificate of analysis.
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- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99
Why source Epitalon from Aeternum Life
Every Epitalon batch is verified by an independent laboratory.
HPLC-tested identity and purity on every Epitalon lot.
Sourced and handled to strict, defined specifications.
Discreet, tracked delivery.
What is Epitalon?
Epitalon (also spelled Epithalon) is a synthetic tetrapeptide — four amino acids, Ala-Glu-Asp-Gly — based on a peptide from the pineal gland. It’s one of the most talked-about molecules in longevity research, largely because of its connection to telomeres and the enzyme telomerase.
Research follows two threads: the telomere angle (telomerase and the DNA caps that shorten with age) and the pineal angle (melatonin and circadian rhythm). Both sit at the heart of aging science. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
Epitalon has an unusual origin. It was not designed from scratch but distilled from epithalamin, a pineal-gland extract studied in Soviet-era gerontology, until the active sequence was narrowed to four residues: Ala-Glu-Asp-Gly. That reduction is what made systematic study possible — a defined tetrapeptide can be synthesised to a specification and characterised, an extract cannot. The published work follows two threads that trace back to the pineal origin: telomerase activity in cultured cells, and the melatonin rhythms that govern the body’s circadian timing.
Research directions
Epitalon is a longevity-research favorite. Here’s where the work focuses.
The headline: Epitalon is studied around telomerase and the DNA caps that shorten as cells age.
It’s derived from a pineal peptide, and the pineal connection is central to its research.
Through the pineal link, it’s studied around melatonin and the body’s day-night rhythm.
Telomere length is a core marker of cellular aging, and that’s Epitalon’s territory.
It’s typically researched in short cycles a few times a year rather than continuously.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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How Epitalon is tested
- Certificate of Analysis (COA) for every Epitalon batch
- HPLC purity & identity
- Mass-spectrometry confirmed
- Batch-tested and fully traceable
Every Epitalon lot is released only after independent verification, so what you receive matches its stated identity and purity.
Handling & Storage
Guidance for handling Epitalon as a laboratory research material.
Store lyophilized Epitalon cold and protected from light, sealed and dry until use.
Handle Epitalon according to standard laboratory practice for research materials.
Each Epitalon batch ships with a batch-specific COA for identity and purity.
Epitalon is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- Epitalon (Epithalon)
- CAS
- 307297-39-8
- Sequence
- Ala-Glu-Asp-Gly
- Appearance
- White lyophilized powder
- Size
- 10 mg / 25 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
What is the difference between Epitalon and epithalamin?
Epithalamin is the original pineal extract — a mixture. Epitalon is the four-residue sequence Ala-Glu-Asp-Gly isolated from it and produced synthetically. The distinction matters for research materials: a defined tetrapeptide can be made to a stated purity and verified by HPLC and mass spectrometry, which is what the COA on this page covers.
What is Epitalon studied for?
It’s studied around telomeres, telomerase, the pineal gland and circadian rhythm. We share these as research directions, not medical claims.
How is it typically used in research?
Epitalon is usually researched in short cycles rather than daily year-round. Reconstitution and cycle guides are shared in our Telegram community.
Is Epitalon for human use?
No. Aeternum Life supplies Epitalon strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for Epitalon?
Yes — every Epitalon batch ships with a batch-specific Certificate of Analysis covering identity and purity.
About Aeternum Life
Aeternum Life is a Japan-inspired peptide brand built on purity, transparency and rigorous testing — the same standard behind the Epitalon on this page. Every product is presented by its composition and backed by batch-specific documentation.
Explore the full Aeternum Life range
Epitalon is one of more than thirty research-grade materials we supply — each one backed by a batch-specific COA and independent testing.
- ✓ Credit card / Apple Pay accepted
- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99