Semax — The Focus Peptide
Semax is a favorite of the nootropic world. Derived from a fragment of ACTH and modified for stability, it’s a short peptide studied for focus, mental clarity and neuroprotection — often linked in research to BDNF, the brain’s own “growth factor.” It is supplied as a lyophilised powder for laboratory reconstitution. Published batch documentation is shown on the COA page when a matching record is available.
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- ✓ Published batch record when available

Why review Semax with Aeternum Life
The listing identifies this item as a laboratory research material.
Identity, format, storage, and package information are shown on the product page.
Destination availability, dispatch details, and tracking are confirmed for the order.
COA records appear by product and batch when a matching record is published.
What is Semax?
Semax is a synthetic peptide based on a fragment of ACTH (adrenocorticotropic hormone), modified for stability. It’s one of the best-known nootropic peptides, studied for how it influences focus, memory and the brain’s resilience.
A recurring thread in Semax research is BDNF (brain-derived neurotrophic factor) — the signal tied to learning and neuronal health — along with focus, mood and neuroprotection. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
Semax comes out of a specific design problem: ACTH(4-10) has interesting effects on the brain but is torn apart by peptidases within minutes. Adding the Pro-Gly-Pro tail — a motif borrowed from other short regulatory peptides — dramatically slows that breakdown, which is what turned a laboratory curiosity into a workable research compound. Because the fragment is the non-hormonal part of ACTH, it carries the neuromodulatory signalling without the adrenal-stimulating activity of the parent hormone. Most published work centres on BDNF and NGF expression, the neurotrophic factors tied to synaptic plasticity.
Research directions

Semax is a cornerstone of nootropic-peptide research. Here’s the focus.
The headline: Semax is studied for attention, mental clarity and cognitive performance.
A recurring theme is BDNF, the brain’s growth factor tied to learning and neuronal health.
It’s researched around protecting neurons under stress.
Cognitive-performance models are a central Semax research area.
It’s also studied around mood and stress resilience.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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Semax documentation
- Published product specification
- Reported purity and test date when available
- Batch number shown on matching records
- Laboratory and verification details only when supplied
The COA page shows the batch documentation currently published. Missing fields are left blank rather than inferred.
Handling & Storage
Guidance for handling Semax as a laboratory research material.
Store lyophilized Semax cold and protected from light, sealed and dry until use.
Handle Semax according to standard laboratory practice for research materials.
Published batch documentation is linked when a matching record is available.
Semax is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- Semax
- CAS
- 80714-61-0
- Appearance
- White lyophilized powder
- Size
- 5 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
What does the Pro-Gly-Pro tail actually do?
It is a stability motif. The bare ACTH(4-10) fragment is degraded by peptidases almost immediately, so the tripeptide tail was added to protect the molecule from enzymatic cleavage and extend how long it survives in solution. Its role is pharmacokinetic rather than functional — the neuromodulatory signalling comes from the ACTH fragment itself.
What is Semax studied for?
It’s studied around focus, BDNF, memory, neuroprotection and mood. We share these as research directions, not medical claims.
How is it used in research?
Semax ships as a freeze-dried powder with a batch-specific COA, reconstituted in the laboratory before use.
Is Semax for human use?
No. Aeternum Life supplies Semax strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for Semax?
Published COA records are available by product and batch when a matching record exists. Laboratory and verification details appear only when stated in that record.

About Aeternum Life
Aeternum Life Limited publishes clearly labeled laboratory research materials and accessories, with specifications and available batch documentation.
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Semax is part of the Aeternum Life research catalog. Review its intended-use status, specifications, and any currently published batch record before ordering.
Bulk price for 3+ vials · stock & delivery time — usually replies within a few hours
- ✓ Available payment methods confirmed in cart
- ✓ Published batch record when available
