Semax — The Focus Peptide
Semax is a favorite of the nootropic world. Derived from a fragment of ACTH and modified for stability, it’s a short peptide studied for focus, mental clarity and neuroprotection — often linked in research to BDNF, the brain’s own “growth factor.” It is supplied as a lyophilised powder for laboratory reconstitution. Every batch is independently third-party tested for purity and ships with its own certificate of analysis.
- ✓ Credit card / Apple Pay accepted
- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99
Why source Semax from Aeternum Life
Every Semax batch is verified by an independent laboratory.
HPLC-tested identity and purity on every Semax lot.
Sourced and handled to strict, defined specifications.
Discreet, tracked delivery.
What is Semax?
Semax is a synthetic peptide based on a fragment of ACTH (adrenocorticotropic hormone), modified for stability. It’s one of the best-known nootropic peptides, studied for how it influences focus, memory and the brain’s resilience.
A recurring thread in Semax research is BDNF (brain-derived neurotrophic factor) — the signal tied to learning and neuronal health — along with focus, mood and neuroprotection. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
Semax comes out of a specific design problem: ACTH(4-10) has interesting effects on the brain but is torn apart by peptidases within minutes. Adding the Pro-Gly-Pro tail — a motif borrowed from other short regulatory peptides — dramatically slows that breakdown, which is what turned a laboratory curiosity into a workable research compound. Because the fragment is the non-hormonal part of ACTH, it carries the neuromodulatory signalling without the adrenal-stimulating activity of the parent hormone. Most published work centres on BDNF and NGF expression, the neurotrophic factors tied to synaptic plasticity.
Research directions
Semax is a cornerstone of nootropic-peptide research. Here’s the focus.
The headline: Semax is studied for attention, mental clarity and cognitive performance.
A recurring theme is BDNF, the brain’s growth factor tied to learning and neuronal health.
It’s researched around protecting neurons under stress.
Cognitive-performance models are a central Semax research area.
It’s also studied around mood and stress resilience.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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How Semax is tested
- Certificate of Analysis (COA) for every Semax batch
- HPLC purity & identity
- Mass-spectrometry confirmed
- Batch-tested and fully traceable
Every Semax lot is released only after independent verification, so what you receive matches its stated identity and purity.
Handling & Storage
Guidance for handling Semax as a laboratory research material.
Store lyophilized Semax cold and protected from light, sealed and dry until use.
Handle Semax according to standard laboratory practice for research materials.
Each Semax batch ships with a batch-specific COA for identity and purity.
Semax is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- Semax
- CAS
- 80714-61-0
- Appearance
- White lyophilized powder
- Size
- 5 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
What does the Pro-Gly-Pro tail actually do?
It is a stability motif. The bare ACTH(4-10) fragment is degraded by peptidases almost immediately, so the tripeptide tail was added to protect the molecule from enzymatic cleavage and extend how long it survives in solution. Its role is pharmacokinetic rather than functional — the neuromodulatory signalling comes from the ACTH fragment itself.
What is Semax studied for?
It’s studied around focus, BDNF, memory, neuroprotection and mood. We share these as research directions, not medical claims.
How is it used in research?
Semax ships as a freeze-dried powder with a batch-specific COA, reconstituted in the laboratory before use. Reconstitution and handling guides are shared in our Telegram community.
Is Semax for human use?
No. Aeternum Life supplies Semax strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for Semax?
Yes — every Semax batch ships with a batch-specific Certificate of Analysis covering identity and purity.
About Aeternum Life
Aeternum Life is a Japan-inspired peptide brand built on purity, transparency and rigorous testing — the same standard behind the Semax on this page. Every product is presented by its composition and backed by batch-specific documentation.
Explore the full Aeternum Life range
Semax is one of more than thirty research-grade materials we supply — each one backed by a batch-specific COA and independent testing.
- ✓ Credit card / Apple Pay accepted
- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99