LL-37 — The Defense Peptide
LL-37 is your body’s own front-line defender — the only human cathelicidin, a 37-amino-acid antimicrobial peptide that’s part of innate immunity’s first response. Research looks at it as a natural “broad-spectrum” peptide and a player in wound healing. Published batch documentation is shown on the COA page when a matching record is available.
Why review LL-37 with Aeternum Life
The listing identifies this item as a laboratory research material.
Identity, format, storage, and package information are shown on the product page.
Destination availability, dispatch details, and tracking are confirmed for the order.
COA records appear by product and batch when a matching record is published.
What is LL-37?
LL-37 (Cathelicidin) is a 37-amino-acid antimicrobial peptide — the only cathelicidin the human body produces. It’s part of the innate immune system’s first line of defense, and its name comes from its two leading leucines (LL) and 37-residue length.
Research centers on LL-37’s natural antimicrobial activity, its role in innate immunity, and its involvement in wound healing and biofilms. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
LL-37 is the only cathelicidin humans make. It is stored as an inactive precursor, hCAP18, and released as the mature 37-residue peptide when proteases cut it free at a site of injury or infection. In solution it folds into an amphipathic α-helix — one face charged, the other hydrophobic — and that geometry is what lets it insert into and disrupt bacterial membranes. But membrane activity is only half the story: the same peptide acts as a signalling molecule, recruiting immune cells and participating in angiogenesis and wound closure, which is why it sits at the boundary between antimicrobial and repair research.
Research directions
LL-37 is a natural defense peptide, and research follows that role. Here’s the focus.
The headline: LL-37 is studied as a natural, broad-acting antimicrobial peptide.
It’s part of the body’s first-response defense, a central theme in the research.
LL-37 is also studied around wound-healing and tissue models.
A recurring focus is its interaction with microbial biofilms.
Beyond direct defense, it’s studied as a signaling molecule in innate immunity.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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LL-37 documentation
- Published product specification
- Reported purity and test date when available
- Batch number shown on matching records
- Laboratory and verification details only when supplied
The COA page shows the batch documentation currently published. Missing fields are left blank rather than inferred.
Handling & Storage
Guidance for handling LL-37 as a laboratory research material.
Store lyophilized LL-37 cold and protected from light, sealed and dry until use.
Handle LL-37 according to standard laboratory practice for research materials.
Published batch documentation is linked when a matching record is available.
LL-37 is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- LL-37 (Cathelicidin)
- CAS
- 154947-66-7
- Appearance
- White lyophilized powder
- Size
- 5 mg / 10 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
Why is LL-37 described as both antimicrobial and immunomodulatory?
Because it does two structurally distinct jobs. Its amphipathic helix physically disrupts microbial membranes, while the same molecule also acts as a host-defence signal — attracting immune cells and taking part in wound-closure and blood-vessel formation. Research treats these as separate functions of one peptide rather than two versions of the same effect.
What is LL-37 studied for?
It’s studied around antimicrobial activity, innate immunity, wound healing and biofilms. We share these as research directions, not medical claims.
How is it handled?
LL-37 ships as a freeze-dried powder with a batch-specific COA.
Is LL-37 for human use?
No. Aeternum Life supplies LL-37 strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for LL-37?
Published COA records are available by product and batch when a matching record exists. Laboratory and verification details appear only when stated in that record.
About Aeternum Life
Aeternum Life Limited publishes clearly labeled laboratory research materials and accessories, with specifications and available batch documentation.
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LL-37 is part of the Aeternum Life research catalog. Review its intended-use status, specifications, and any currently published batch record before ordering.
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