Thymosin β4 — The Full-Length Repair Protein
If TB-500 is the famous fragment, Thymosin β4 is the complete original — the full 43-amino-acid protein your body actually makes to organize repair. It’s the master actin regulator behind cell movement, wound healing and tissue regeneration, studied everywhere from muscle and skin to the heart. Every batch is independently third-party tested for purity and ships with its own certificate of analysis.
- ✓ Credit card / Apple Pay accepted
- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99
Why source Thymosin β4 from Aeternum Life
Every Thymosin β4 batch is verified by an independent laboratory.
HPLC-tested identity and purity on every Thymosin β4 lot.
Sourced and handled to strict, defined specifications.
Discreet, tracked delivery.
What is Thymosin β4?
Thymosin β4 (TB4) is a naturally occurring 43-amino-acid protein found throughout the body — and TB-500 is a synthetic fragment of it. Where TB-500 copies the active region, TB4 is the whole molecule: the body’s own master organizer of actin, the scaffolding cells use to move, build and repair.
As the full-length protein, TB4 is researched across the widest range of repair processes — wound and skin healing, muscle and connective tissue, cardiac tissue, even hair and eye models. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
Two distinctions matter with this molecule. The first is against Thymosin α1: despite the shared name they belong to unrelated protein families — α1 is a 28-residue immune-signalling peptide studied around Toll-like receptors, β4 is a 43-residue actin-binding protein studied around cell movement. The second is against TB-500, which is the short active fragment rather than the whole protein. Full-length β4 is the cell’s principal G-actin sequestering protein: it holds monomeric actin in reserve and governs how quickly the cytoskeleton can be rebuilt, which is what puts it at the centre of cell-migration research.
Research directions
Thymosin β4 is the complete repair protein, and research reaches across the whole repair story. Here’s the focus.
TB4’s core job: managing actin, the cellular scaffold behind movement, structure and repair.
A central theme — TB4 is heavily studied in wound- and skin-repair models.
Like its TB-500 fragment, TB4 is researched for muscle and connective-tissue recovery.
Some of the most cited TB4 work looks at heart tissue and regeneration.
TB4 is the complete 43-residue protein; TB-500 is its active fragment — the same story at different scales.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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How Thymosin β4 is tested
- Certificate of Analysis (COA) for every Thymosin β4 batch
- HPLC purity & identity
- Mass-spectrometry confirmed
- Batch-tested and fully traceable
Every Thymosin β4 lot is released only after independent verification, so what you receive matches its stated identity and purity.
Handling & Storage
Guidance for handling Thymosin β4 as a laboratory research material.
Store lyophilized Thymosin β4 cold and protected from light, sealed and dry until use.
Handle Thymosin β4 according to standard laboratory practice for research materials.
Each Thymosin β4 batch ships with a batch-specific COA for identity and purity.
Thymosin β4 is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- Thymosin β4 (full-length, TB4)
- CAS
- 77591-33-4
- Appearance
- White lyophilized powder
- Size
- 10 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
How is full-length Thymosin β4 different from TB-500?
TB-500 is the short active fragment; Thymosin β4 is the complete 43-residue protein. The full-length form is the cell’s principal G-actin sequestering protein and carries binding regions the fragment does not, which is why research on the two is not interchangeable even though they are often discussed together.
What is Thymosin β4 studied for?
As the full-length repair protein, it’s studied around actin, wound and tissue healing, muscle and cardiac models. We share these as research directions, not medical claims.
How is it different from TB-500?
TB4 is the complete 43-amino-acid protein; TB-500 is a synthetic fragment of its active region. Reconstitution and handling guides for both are shared in our Telegram community.
Is Thymosin β4 for human use?
No. Aeternum Life supplies Thymosin β4 strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for Thymosin β4?
Yes — every Thymosin β4 batch ships with a batch-specific Certificate of Analysis covering identity and purity.
About Aeternum Life
Aeternum Life is a Japan-inspired peptide brand built on purity, transparency and rigorous testing — the same standard behind the Thymosin β4 on this page. Every product is presented by its composition and backed by batch-specific documentation.
Explore the full Aeternum Life range
Thymosin β4 is one of more than thirty research-grade materials we supply — each one backed by a batch-specific COA and independent testing.
- ✓ Credit card / Apple Pay accepted
- ✓ Third-party COA included
- ✓ Free worldwide shipping over $99