Thymosin β4 — The Full-Length Repair Protein
If TB-500 is the famous fragment, Thymosin β4 is the complete original — the full 43-amino-acid protein your body actually makes to organize repair. It’s the master actin regulator behind cell movement, wound healing and tissue regeneration, studied everywhere from muscle and skin to the heart. Published batch documentation is shown on the COA page when a matching record is available.
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Why review Thymosin β4 with Aeternum Life
The listing identifies this item as a laboratory research material.
Identity, format, storage, and package information are shown on the product page.
Destination availability, dispatch details, and tracking are confirmed for the order.
COA records appear by product and batch when a matching record is published.
What is Thymosin β4?
Thymosin β4 (TB4) is a naturally occurring 43-amino-acid protein found throughout the body — and TB-500 is a synthetic fragment of it. Where TB-500 copies the active region, TB4 is the whole molecule: the body’s own master organizer of actin, the scaffolding cells use to move, build and repair.
As the full-length protein, TB4 is researched across the widest range of repair processes — wound and skin healing, muscle and connective tissue, cardiac tissue, even hair and eye models. Aeternum Life supplies it as ultra-high-purity research material with a batch-specific Certificate of Analysis on every order.
Two distinctions matter with this molecule. The first is against Thymosin α1: despite the shared name they belong to unrelated protein families — α1 is a 28-residue immune-signalling peptide studied around Toll-like receptors, β4 is a 43-residue actin-binding protein studied around cell movement. The second is against TB-500, which is the short active fragment rather than the whole protein. Full-length β4 is the cell’s principal G-actin sequestering protein: it holds monomeric actin in reserve and governs how quickly the cytoskeleton can be rebuilt, which is what puts it at the centre of cell-migration research.
Research directions

Thymosin β4 is the complete repair protein, and research reaches across the whole repair story. Here’s the focus.
TB4’s core job: managing actin, the cellular scaffold behind movement, structure and repair.
A central theme — TB4 is heavily studied in wound- and skin-repair models.
Like its TB-500 fragment, TB4 is researched for muscle and connective-tissue recovery.
Some of the most cited TB4 work looks at heart tissue and regeneration.
TB4 is the complete 43-residue protein; TB-500 is its active fragment — the same story at different scales.
For research purposes only. These materials are not drugs or dietary supplements and are not intended to diagnose, treat, cure or prevent any disease.
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Thymosin β4 documentation
- Published product specification
- Reported purity and test date when available
- Batch number shown on matching records
- Laboratory and verification details only when supplied
The COA page shows the batch documentation currently published. Missing fields are left blank rather than inferred.
Handling & Storage
Guidance for handling Thymosin β4 as a laboratory research material.
Store lyophilized Thymosin β4 cold and protected from light, sealed and dry until use.
Handle Thymosin β4 according to standard laboratory practice for research materials.
Published batch documentation is linked when a matching record is available.
Thymosin β4 is supplied strictly for laboratory and research use. Not for human or veterinary consumption; no administration or dosing guidance is provided.
Specifications
- Name
- Thymosin β4 (full-length, TB4)
- CAS
- 77591-33-4
- Appearance
- White lyophilized powder
- Size
- 10 mg per vial
- Purity
- ≥ 99% (HPLC, see COA)
- Storage
- Store at 2–8°C, protect from light
For research use. Not intended to diagnose, treat, cure or prevent any disease.
Frequently asked questions
How is full-length Thymosin β4 different from TB-500?
TB-500 is the short active fragment; Thymosin β4 is the complete 43-residue protein. The full-length form is the cell’s principal G-actin sequestering protein and carries binding regions the fragment does not, which is why research on the two is not interchangeable even though they are often discussed together.
What is Thymosin β4 studied for?
As the full-length repair protein, it’s studied around actin, wound and tissue healing, muscle and cardiac models. We share these as research directions, not medical claims.
How is it different from TB-500?
TB4 is the complete 43-amino-acid protein; TB-500 is a synthetic fragment of its active region.
Is Thymosin β4 for human use?
No. Aeternum Life supplies Thymosin β4 strictly as a research-grade material for laboratory research. It is not sold for human or veterinary consumption.
Is a COA available for Thymosin β4?
Published COA records are available by product and batch when a matching record exists. Laboratory and verification details appear only when stated in that record.

About Aeternum Life
Aeternum Life Limited publishes clearly labeled laboratory research materials and accessories, with specifications and available batch documentation.
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Thymosin β4 is part of the Aeternum Life research catalog. Review its intended-use status, specifications, and any currently published batch record before ordering.
Bulk price for 3+ vials · stock & delivery time — usually replies within a few hours
- ✓ Available payment methods confirmed in cart
- ✓ Published batch record when available
